'We still depend on ourselves. Our margin for error has run out and we are aware of the challenge.'
The 28-year-old did not reveal where he would be playing next but widespread reports in the Spanish media said he would be joining Barcelona.
With the distraction of two individual scoring records safely out of the way, Barcelona forward Lionel Messi can turn his full focus on helping the club win the major silverware that eluded them last season.
United have struggled this season, collecting 10 points from their opening seven Premier League matches and being dumped out of the League Cup by second-tier Derby County.
Cristiano Ronaldo admits that he suffered for pushing himself too much at the end of last season but is now close to his best as Real Madrid prepare to face Real Sociedad this weekend.
Cristian Tello hit a hat-trick as Barcelona came from behind to win 4-1 in their King's Cup quarter-final first leg at Levante on Wednesday and Lionel Messi celebrated his 400th appearance for the Catalan side.
Moffi penalty gives Lorient 1-0 win over Monaco.
A summary of all the Champions League matches played across Europe on Wednesday
Cristiano Ronaldo took his tally for the La Liga season to a phenomenal 13 goals in six appearances with his third treble of the campaign as Real Madrid romped to a 5-0 win at home to Athletic Bilbao on Sunday.
Antoine Griezmann and Yannick Carrasco each conjured moments of magic as Atletico Madrid recaptured top spot in La Liga from Barcelona with a hard-fought 2-0 victory at Celta Vigo on Sunday.
The Frenchman, voted the world's third best player of 2016, has been the subject of intense transfer speculation since signing a new contract with Atletico in May 2017.
News of all that's transpired on and off the football field
IMAGES from Europa League matches played on Thursday.
News of all that's transpired on and off the football field on Thursday
Seven-times champions AC Milan, knocked out of the Champions League by Barcelona in the last two seasons, were drawn against the Catalans again in the group stage of this season's competition on Friday.
Real Sociedad midfielder Carlos Vela was called up by Mexico for November tour friendlies on Tuesday after turning his back on his country since March 2011.
Images from the English Premier League matches played on Saturday.
Rejected former boss David Moyes says Manchester United must not become a club that are continuously sacking managers and should give his under-fire successor Louis van Gaal time to build a successful side.
Atletico Madrid's French forwards Antoine Griezmann and Kevin Gameiro fired them to a first win in three league outings as they beat Valencia 3-0 on Sunday to maintain their hold on Spain's fourth Champions League qualifying place.
Barcelona have been boosted by the successful return from injury of talismanic playmaker Andres Iniesta as they prepare to host city rivals Espanyol in La Liga on Sunday.
A summary of Thursday's matches in the Europa League.
Barcelona moved ever closer towards a successful defence of their La Liga title after nearest challengers Atletico Madrid suffered a shock late collapse at struggling Sporting Gijon to lose 2-1 on Saturday.
Joao Miranda and new signing Mario Mandzukic led Atletico Madrid to a 2-1 home win in La Liga on Saturday as visitors Eibar were unable to cope with the aerial threat of the champions.
Following a bright start to the season it was another disappointing display by Villarreal, who have one win from seven games in La Liga, before the return at El Madrigal in two weeks.
News of all that's transpired on and off the football field
The three-horse race for the La Liga title tightened on Sunday when leaders Real Madrid drew 2-2 at city rivals Atletico and Barcelona won 4-1 at home to Almeria.
Manchester City have signed Chile goalkeeper Claudio Bravo from Barcelona on a four-year contract for an initial 18 million euros (15.37 million pounds), the clubs confirmed on Thursday.
Atletico Madrid coach Diego Simeone praised the 'decisive' Antoine Griezmann after his two goals helped down Olympique de Marseille 3-0 in the Europa League final on Wednesday and tried to convince the striker to resist the lure of Barcelona.
Wales coach Chris Coleman conceded on Thursday that a stoppage-time loss to England was the low point of his career, but he said he could take inspiration from Roy Hodgson's side who had also come back from deep disappointment. Wales led at halftime after a sensational long-range Gareth Bale free kick, but lost 2-1 after Jamie Vardy's equaliser and Daniel Sturridge's winner in the 92nd minute. Asked whether this was the low point of a career that has included spells in charge at Fulham, Real Sociedad and Greek side Larissa in Greece, Coleman responded: "I'd have to say yes to be honest.
Luis Enrique's new task is to rebuild a Spain team that ruled international football between 2008 and 2012 by winning successive European Championships and the 2010 World Cup but have been deeply disappointing at their last three international tournaments.
Chelsea's Marcos Alonso and Real Madrid's Nacho were notable absentees in defence, along with Atletico Madrid midfielder Koke.
La Liga leaders Barcelona hit two goals in the final three minutes to earn a 3-2 win at Rayo Vallecano
As Barca prepare for a trip to Madrid to play Rayo Vallecano on Saturday, they are still reeling from Tuesday's 3-2 Champions League reverse at Paris St Germain, when their defence was badly exposed by the Ligue 1 title holders.
News of all that transpired on and off the football field.
Champions Liverpool suffered a shock 1-0 defeat to lowly Burnley on Thursday, ending their 68 match unbeaten home record in the Premier League as their title defence continued to fade.
Images from football matches played across Europe.
Here are five talking points from the weekend in La Liga.
News of all that transpired on and off the football field.
La Liga leaders Barcelona drew 0-0 at Huesca on Saturday and are nine points clear of second-placed Atletico Madrid, who cut the gap by beating Celta Vigo 2-0.
